Unveiling Genetic Switches for All
Gain unparalleled insights into the epigenetic landscape to shape the future of healthcare and personalized medicine.
Our Epigenomics Capabilities
In the realm of personalized medicine, understanding the intricate dance between genetics and environmental factors is key. Epigenomics, the study of changes in gene activity that do not involve alterations to the DNA sequence, plays a crucial role in disease mechanisms, development, and environmental responses.
DNA Methylation Analysis
Analyze genome-wide or targeted DNA methylation patterns to understand their role in gene regulation and disease.
- Global DNA Methylation Profiling (WGBS, RRBS, EPIC arrays)
- Targeted Methylation Analysis for specific genomic regions
- Differential Methylation Analysis between conditions
- Identification of Differentially Methylated Regions (DMRs)
Histone & Chromatin Analysis
Investigate the key regulators of gene expression through analysis of histone modifications and chromatin accessibility.
- Histone Modification Analysis (ChIP-Seq for H3K4me3, H3K27ac, H3K27me3, etc.)
- Identification and Clustering of Histone Marks
- Chromatin Accessibility Analysis (ATAC-Seq, DNase-Seq)
- Chromatin State Segmentation and Enhancer Prediction
Integrative & Functional Analysis
Connect epigenetic changes to biological function. We integrate multiple data types to build a comprehensive picture of gene regulation.
- Integrative Epigenomic Analysis (Multi-Omics Integration)
- Correlation and Network Analysis with transcriptomic data
- Functional Enrichment and Pathway Analysis
- Advanced Data Visualization Services (circos plots, heatmaps, genome browsers)
Our Epigenomics Analysis Workflow
Quality Control & Preprocessing
Comprehensive QC including adapter trimming, quality filtering, and bias correction.
Alignment & Peak Calling
Read alignment to reference genome and identification of enriched regions.
Differential Analysis
Statistical analysis to identify significant epigenetic changes between conditions.
Functional Interpretation
Annotation, pathway analysis, and integration with other omics data.
Unlock the Secrets of the Epigenome
Contact us to learn how our epigenomics services can advance your research and contribute to the future of precision medicine.
Frequently Asked Questions
Find answers to common questions about our epigenomics services and processes.